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Mansoura Veterinary Medical Journal

Document Type

Original Article

Keywords

Rabbits; Nigella sativa oil; Aloe Vera gel; antioxidant enzymes

Abstract

Objective: This study aimed to analyze the oxidative parameters of Nigella sativa and Aloe Vera gels in rabbits. Design: Randomized controlled experimental study. Animals: Fifteen rabbits weigh 1.5 ±0.5 kg. Procedures: Rabbits were allocated to one of three groups of five animals each. The first group served as the control group, while rabbits in the second group were administered 400 mg/kg Nigella sativa oil (100%). The third group was given an aqueous extract of 10% w/v of 15 ml ⁄ L Aloe Vera gel. All treatments were administered daily for two successive weeks. Blood samples were collected from the ear vein of each rabbit to determine the antioxidant status on 1st day, 1st week, and 2nd week after treatment. Results: The obtained results showed that administration of Nigella sativa oil and Aloe Vera gel improved antioxidant activity by increasing catalase, reducing glutathione, and decreasing malondialdehyde levels in rabbits post-treatment. Conclusion and clinical relevance: Our data highlight that using Nigella sativa and Aloe Vera gel are good supplements for rabbits without any adverse effects.

Receive Date

22 December 2021

Accept Date

10 October 2022

Publication Date

2023

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