Mansoura Veterinary Medical Journal

Efficacy of Ginger and Nutritox® in counteracting aflatoxin effects on white Pekin ducklings

Walaa Abu El-Ela, Veterinary Teaching Hospital, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt.
Kamel Abou.Elazm, Departments of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt
Sanaa Awad, Departments of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt

Corresponding Author

Abu El-Ela, Walaa

Document Type

Original Article

Subject Areas

Pharmacology and toxicology

Keywords

Aflatoxin, duckling, Ginger, Nutritox®, antioxidants, histopathology

Abstract

Objective: To evaluate the anti-aflatoxin effects of Ginger and Nutritox® in white Pekin ducklings. Design: Randomized experimental study Animals: Ninty- one-day-old white Pekin ducklings. Procedures: Ducklings were alienated randomly into six equal groups, each group in 3 replicates (each replicate, n=5). Control group G1) was fed on commercial broiler basal diet without any medications, while other experimental groups, namely 2, 3, 4, 5 and 6 were received diet containing: G2) basal diet (BD) + 300 ppb AF (aflatoxin); G3) BD + 300 ppb AF + 250 mg kg-1 Gr (Ginger); G4) BD +300 ppb AF +1gm/kg feed Nutritox®; G5) BD + 250 mg kg-1 mg/kg of B.W Gr; G6) BD + 1gm/kg feed Nutritox® during study (1-14) days respectively. Results: Results showed that, addition of Ginger and Nutritox® ameliorated in different degrees the adverse effects of aflatoxin and improved growth performance and some serum biochemical parameters [Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and Alkaline phosphatase (ALP)]. They hasten the recovery of antioxidant enzymes (MDA and GSH) in tissue to their normal levels during certain periods of our experiments. Histopathological liver changes run in the same track with biochemical results. Results revealed that administration of Ginger or Nutritox® in diet prevents and/or reduce some adverse effects of aflatoxin in ducks. Conclusion and clinical relevance: Our study indicates that ginger, an alternative natural product can provide protection against aflatoxin as Nutritox®.

How to Cite This Article

Abu El-Ela, Walaa; Abou.Elazm, Kamel; and Awad, Sanaa (2019) "Efficacy of Ginger and Nutritox® in counteracting aflatoxin effects on white Pekin ducklings," Mansoura Veterinary Medical Journal: Vol. 20: Iss. 4, Article 2.
DOI: https://doi.org/10.21608/mvmj.2019.20.404